Is cholesterol hereditary? what familial hypercholesterolemia tells us

High cholesterol is a problem that involves about 2.5 million peoples, both men, and women. When the values of total cholesterol exceed the limit of 200 mg/dl (milligrams per deciliter). A first alarm is triggered for our body, in particular. If the LDL (the fraction of bad cholesterol) is high.

It is, therefore, necessary to assess the possible risk of developing ischemic heart disease, considered the first cause of death from cardiovascular diseases. Some individuals also have high values of LDL while following a proper lifestyle is the case of ‘ hypercholesterolemia family, a hereditary condition to be reckoned with. Here is the discussion about cholesterol hereditary.

What is ‘the’ hypercholesterolemia family

L ‘ hypercholesterolemia family is a disease that can present in two forms: the first, rarest, called homozygously and the second most common, called heterozygously. Both conditions derive from a series of mutations in the LDL receptor gene. Which is located on chromosome 19 and which prevents the body from properly disposing of bad cholesterol circulating in the blood.

Characterized by high levels of total cholesterol (but not triglycerides), the hereditary form can develop more or less severe depending on the number of mutations involved. In the homozygous form. It manifests itself seriously from infancy: fat deposits are formed (defined as xanthomas) inside the skin, on the elbows, knees, and buttocks. But also in the tendons and around the corner of the eye (horny arches). Furthermore, total cholesterol values are between 600 and 1200 mg / dL. It is a hereditary problem. And to suffer from it it is enough to have only a mutated copy of the gene that should help to dispose of the bad cholesterol.

Heterozygous subjects, on the other hand, have milder manifestations. Often not very evident during childhood. The problems affecting the cardiovascular system generally begin around the age of 35-40 in men and around 45-55 years in women.

Diagnosis and treatment for the ‘ hypercholesterolemia familyIs cholesterol hereditary? what familial hypercholesterolemia tells us

The diagnosis to establish the presence of hereditary hypercholesterolemia is based on three fundamental points:

– family history analysis
– clinical manifestations
– laboratory tests

Those who suffer from hypercholesterolemia family is to maintain a healthy lifestyle, getting regular physical activity, not smoking, avoiding alcohol abuse, controlling all risk factors and, crucially, by following a healthy diet. Moreover, through medical consultation, it will be possible to combine these healthy policies with the right drug therapy.


Currently, a drug therapy statin can effectively cure the ‘ hypercholesterolemia family. And prevent long-term cardiovascular consequences. The main limitation that is found in the use of drugs is the adherence by the patient therapy: often, it comes to a clinical long-term process that requires careful monitoring by both the physician and the assisted.

Nutrition and lifestyleIs cholesterol hereditary? what familial hypercholesterolemia tells us

Feeding is an essential point to keep cholesterol at bay so it is good to choose foods based on their effectiveness. And in some cases also makes use of specific food supplements, for example, based on live milk enzymes and fermented red rice. The combined action of probiotics that promote the balance of intestinal bacterial flora, together with monacolin k, a substance produced by the fermentation of red rice, helps to maintain normal blood cholesterol levels.

However, it is advisable to consume low-fat, high-fiber foods (especially of the soluble type found in legumes, fruit, vegetables, and whole grains) to maintain LDL cholesterol as normal.

Regarding lifestyle, weight control and physical activity remain two preferred behaviors. Practicing, at least 3-4 times a week, anaerobic training of at least 40 minutes helps our body not only to keep fit but also to significantly reduce the possibility of incurring heart disease. Go ahead then to walk, run, swim and exercise bike always with appropriate precautions and avoiding excessive loads.


Hi, I am JEFFREY Dawson; I am an entrepreneur, father, mentor, and adventurer passionate about life. At this moment, I am working with depression and anxiety.

You May Also Like

More From Author

+ There are no comments

Add yours

This site uses Akismet to reduce spam. Learn how your comment data is processed.